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Introduction to ferulic acid

Ferulic Acid, with the chemical name of 4-hydroxy-3-methoxycinnamic acid, is one of the derivatives of cinnamic acid (also known as cinnamic acid, 3-phenyl-2-acrylic acid, molecular structure). Ferulic acid was initially found in seeds and leaves of plants. It is a phenolic acid widely existing in plants. Barley Grass Powder combines with polysaccharides and proteins in cell wall to form the skeleton of cell wall.

Its content in ferula, Gardenia Yellow, chuanxiong, Cimicifuga, Zizyphus Spinosae and other traditional Chinese medicine is high, which is one of the effective components of these traditional Chinese medicine, and has been used as one of the quality indicators of Chinese patent medicine. The content of Mangiferin in coffee, rice husk, vanilla bean, wheat bran and rice bran was also higher. In recent years, many ferulic acid and its derivatives have been found to have pharmacological and biological activities with low toxicity. Therefore, they are widely used in medicine, health care products, cosmetics raw materials and food additives.

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What are the influencing factors of gardenia yellow

In the UV visible region, there are three absorption peaks of gardenia yellow in aqueous solution: 238nm, 325nm and 440nm, which are the characteristic absorption peaks of geniposide, chlorogenic acid, Flax lignans and crocetin respectively.

Food Colour Crocus Sativus solution is orange yellow at pH 1 ~ 7 and bright yellow at pH 8 ~ 12. The stability of the pigment was poor under acidic conditions, but good under neutral and alkaline conditions. Similar to other carotenoids, gardenia yellow had poor sunlight tolerance. Except for Fe and Cu, common metal ions had no effect on Gardenia yellow.

When gardenia yellow solution coexists with oxidant, Mangiferin will fade due to oxidation. Therefore, if gardenia yellow is used in food, it is necessary to avoid contact with oxidants during processing and storage, so as to delay or reduce the fading of gardenia yellow.

In the food system with Beet Root Powder as dye, ascorbic acid and sodium isoascorbate can significantly delay the color fading. Therefore, on the premise of not affecting the flavor and other quality indexes of the product, proper amount of antioxidant can be added to prevent or delay the fading of gardenia yellow.

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Antibacterial and antiviral functions of ferulic acid

Hirabayashi et Capsicum Oleoresin. Found that after the megaphilic cells of experimental mice were infected with influenza virus, the blank control was set without treatment, and the experimental group was treated with ferulic acid and isoferulic acid. Analysis of the results showed that the production of interferon in the experimental group decreased rapidly. In recent years, there are many reports that ferulic acid has a significant inhibitory effect on influenza virus (Barley Grass Powder), respiratory syncytial virus (RSV) and HIV. In the same cell line, the effect of ferulic acid on inflammatory protein was studied. The results showed that ferulic acid could reduce the production of the protein rapidly. Among them, ferulic acid has inhibitory effect on HIV, so it is possible that Sweet Potato Powder may become a future chemotherapeutic agent. It is speculated that the inhibitory mechanism of ferulic acid on virus is related to its ability to reduce the activity of xanthine oxidase. It is suggested that the antibacterial function of Ferulic Acid is mainly due to its strong inhibitory effect on n-ethyluginostase in bacteria.

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Main uses of gardenia yellow(2)

Compared with direct dyeing, the color of the Bitter Melon Extract with post mordant has no obvious change. Except the light fastness is no more than grade 3, the other fastness is basically above grade 4, which is more reduced.

Pharmaceutical industry(Gardenia Yellow)

In addition to Capsicum Oleoresin components that can be colored, the yellow pigment also contains saffron acid with high medical value and high price, such as blood harmonizing, blood activating, fatigue eliminating, pain relieving and N-Acetylneuraminic Acid pressure reducing, which can be applied to the pharmaceutical industry.

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Main uses of gardenia yellow(1)

Food industry

The Gardenia Yellow pigment can inhibit the oxidation of 80% linoleic acid, so it can be used as an antioxidant in food processing. It has good heat resistance, and the residual rate of pigment is more than 85% at 80 ℃ for 120 minutes. In the range of visible light (40lun-700nln), the light irradiation is stable, but the light irradiation is unstable in the range of 250nm-390nm. Therefore, mast Mangiferin can be used as antioxidant and colorant in food industry.

Mast yellow pigment has excellent dyeing ability to protein, starch and so on. It can be widely used in pastry, candy, flour, beverage, Flax lignans, biscuit, ice cream and other foods.

Silk fabric

The results show that natural gardenia yellow can dye silk fabrics. By changing the dyeing conditions, direct dyeing and mordant dyeing were used to dye silk. The optimal dyeing process was obtained by orthogonal test analysis. The results show that gardenia yellow can be directly dyed on silk fabrics, and the amount of dyes has the greatest influence on the dyeing results, Ginkgo Biloba Extract and the dye has better lifting performance. Gardenia yellow is suitable for mordant dyeing.

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The properties of gardenia yellow

Orange yellow crystalline powder, slightly smelly. Synephrine Hcl is easily soluble in water and immediately dissolves into a transparent yellow liquid. It is soluble in ethanol and propylene glycol, but insoluble in oil. PH value has little effect on hue. Its hue is more stable than β – carotene in acid (pH 4 ~ 6) and alkaline (pH 8 ~ 11), especially in alkaline medium. Its color is more bright, and its absorbance is maximum near 440nm. Under neutral or alkaline conditions, Pine Bark Extract has good light and heat resistance, but it has poor heat resistance and light resistance at low pH value, and is easy to browning. It has good dyeing effect on protein and starch, that is, Ginkgo Biloba Extract has good coloring power for hydrophilic food, but it is not stable in aqueous solution. The discoloration is more obvious in acid than in alkali. It is stable to metal ions (such as aluminum, calcium, lead, copper, tin, etc.), and iron ions tend to make Gardenia Yellow and black.

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Anti radiation effect of ferulic acid

Radiation induced organ failure is largely caused by chronic peroxide damage. Radiation damage to the body can be divided into direct damage and Mangiferin. Direct damage directly causes the breakage of some sensitive molecules in the cell; indirect damage causes the radiolysis of water, which leads to the increase of intracellular reactive oxygen species and the change of subcellular structure. Therefore, antioxidants are widely used in the treatment of radiation injury. In order to protect cells from reactive oxygen species (ROS), it is necessary to maintain stable endogenous sulfhydryl pool, especially glutathione (Gardenia Yellow) and nicotinamide adenine dinucleotide phosphate (NADPH). Glutathione provides reduction equivalent for the conversion of hydrogen peroxide and lipid peroxide into water and lipid alcohol, and protects the sulfhydryl protein group from oxidative damage. The rate limiting reaction of glutathione biosynthesis is catalyzed by glutamate cysteine ligase (Flax lignans), which is composed of a catalytic subunit (GCLC) and a regulatory subunit (GCLM). Nicotinamide adenine dinucleotide phosphate is an important antioxidant component in tissues. It can maintain the redox potential of cells by reducing the reduction equivalent of glutathione reductase and thioredoxin.

As a phenolic plant component, Ferulic Acid has strong antioxidant activity, which has a great promoting effect on human health. Ferulic acid can significantly increase the content of glutathione and nicotinamide adenine dinucleotide phosphate in radiation-induced endothelial cells, which has protective effect on irradiated endothelial cells. Heme oxygenase is an antioxidant enzyme. It can convert heme into biliverdin, and finally into antioxidant bilirubin. Ferulic acid can regulate the expression of heme oxygenase, thus playing a protective role in radiation protection.

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The structure and classification of flash Ligans(3)

Lignan lactone

Capsicum Oleoresin lactone is a lactone ring formed by the epoxidation of tetrahydrofuran in monoepoxy lignans. It often coexists with dehydrogenated compounds in the same plant. [structural formula omitted]

For example, arctiin and Spirulina Protein Powder in Fructus Arctii belong to lignan.

Cyclolignans

Ranacenides

Podophyllotoxin

It can clear away heat and toxin, dissipate phlegm and disperse mass, remove phlegm and detumescence, resist cancer and Citrus Aurantium Extract.

Cyclolignans are cyclized from simple lignans. Its representative is isopaclitaxel.

Cyclolignan lactone

Cyclolignolide is synthesized from the intermediate ring of lignan c9-c9 ‘. [podophyllotoxin]

Dicyclohexyl lignans

Cactus Extract is a kind of lignans with two epoxy structures formed by the connection of two phenylpropanoid side chains. The natural bicyclo lignans have CIS linked double parallel tetrahydrofuran rings.

Forsythin and forsythin in Forsythia suspensa are bicyclo lignans.

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The structure and classification of flash Ligans(2)

Simple lignans [basic carbon framework]

Diarylbutanes: Gardenia Yellown

It can clear away heat and diuresis, clear eyes, eliminate accumulation

Sweet Potato Powder is used for hypochondriac pain, abdominal distension, anorexia, nausea and loose stool caused by damp heat of liver and Diosmin.

Monoepoxy lignans

Oleoresin

In addition to the 8-8 ‘connection, there are 7-0-7’, 9-0-9 ‘, 7-0-9’ epoxy structure (forming furan or tetrahydrofuran ring). [N-Acetylneuraminic Acid] its representative substances are solanine and oleoresin.

It contains high efficiency Anti Wrinkle Essence, which can quickly moisturize and replenish moisture.

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The structure and classification of flash Ligans(1)

Mangiferin exist in plants, belonging to a kind of phytoestrogen, which has the function of scavenging free radicals and antioxidation. Lignans are also found in grains (such as rye, wheat, oats, Gardenia Yellow, etc.), soybeans and cruciferous plants (such as broccoli) and some fruits (such as strawberries). Lignans can bind estrogen receptors and interfere with cancer promoting effect. Therefore, Sweet Potato Powder may have preventive and therapeutic effects on breast cancer, prostate cancer and colon cancer.

Lignans are a kind of natural components which are polymerized by phenylpropanoid bimolecular polymerization. There are four monomers of lignans: ① cinnamic acid and occasionally cinnamaldehyde. ② N-Acetylneuraminic Acid. ③ Propylene benzene. ④ Allyl benzene.

Phyllanthin

Classification basis: according to the basic carbon frame and condensation of lignans.

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