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Introduction to the functions of citrus aurantium extract(1)

Synephrine is the main active component in the fruit of lime. Citrus Aurantium Extract can effectively prevent excess energy (heat accumulation), regulate qi by wind, warm stomach, promote appetite and accelerate metabolism. In theory, lime can accelerate fat metabolism and will not have adverse side effects on cardiovascular system like the patients using ephedra. White Kidney Bean Extract is also a mild fragrant expectorant, a neurotranquilizer and a laxative for constipation.

Lose weight

The most likely explanation for the weight loss function of lime extract is the amphetamine like effect of alkaloids. Although this effect is likely to be slightly less active than ephedrine (Flax lignans), and less active than ephedrine, users can expect variable effects including consumption of excess calories, decreased appetite and increased satiety, all of which may lead to weight loss. A study of dogs has also shown that synephrine can increase metabolic rate in special fatty tissue called brown fat tissue.

Due to the fact that synephrine and other components in trifoliate are structurally similar to ephedrine and act as special adrenaline receptor agonists (N-Acetylneuraminic Acid, but not Beta-1, Beta-2 or Alpha-1), trifoliate does not have the same negative effect on the central nervous system as ephedra. Ephedra will stimulate all the beta adrenoceptors.

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The effect of bitter melon extract

Balsam pear element was originally made by processing balsam pear extract, but the effect and effect of Gardenia Yellow pear element are superior to balsam pear, because it is more simple to be absorbed by human body after concentration(Mangiferin); besides the effect of clearing away heat, detoxification and eyesight, there are many pharmacological effects;

Bitter Melon Extract element was originally made by processing balsam pear extract, but the effect and effect of balsam pear element are superior to balsam pear, because Mixed Tocopherols Oil is more simple to be absorbed by human body after concentration; besides the effect of clearing away heat, detoxification and eyesight, there are many pharmacological effects;

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Preparation of mango leaf extract toothpaste

At present, the new health care products or drugs developed with Mango Leaf Extract as the main component are generally oral preparations. Because the bioavailability of mangiferin is very low, the clinical trial effect of these preparations is not ideal.

A. Glue making: according to the amount in the Gardenia Yellow, put glycerin, 70% sorbitol solution, xanthan gum and sodium carboxymethylcellulose into the glue making pot, stir at high speed for 7 minutes, then add water, xylitol, sodium pyrophosphate, potassium sorbate and citric acid, continue to stir until Ginkgo Biloba Extract is colloidal, stand for 6 hours, and then stir at high speed for 20 minutes to get transparent and uniform glue.

B. Kneading: pour the glue into the kneader, add other components in the formula, mix evenly, and get the sticky paste.

C. Grinding: put the paste into the colloid mill and grind until Red Beet Root Powder becomes a uniform and soft paste.

D. Aging: transfer the ground paste into a temporary storage tank, and allow it to stand for 12 hours, so that the bubbles in the paste will be discharged, and the paste will become more viscous and uniform.

E. Vacuum degassing: pour the aged paste into the vacuum degasser, and turn on the machine to remove the bubbles in the paste.

F. Filling: put the vacuum degassed paste into the automatic filling machine, separately put it into the toothpaste tube, and then seal the tail to get the product mango leaf extract toothpaste.

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Detection and analysis method of ferulic acid(2)

3. Thin layer spectrophotometer method

The qualitative analysis of Ferulic Acid extracted from rye bran was carried out by tlc-spectrophotometry. The developing agent was dichloromethane: acetonitrile: formic acid = 75:25:10. The quantitative analysis was carried out by Flax lignans. The results showed that although the spectrophotometer was easily interfered by other components, the relative error of Capsicum Oleoresin was about 7%, and the reproducibility was good 。

4. High performance capillary electrophoresis

Capillary zone electrophoresis is the most widely used separation mode. Features simple, efficient, fast, less sample consumption, Sweet Potato Powder. The content of ferulic acid in angelica preparation was determined by hollow fused quartz capillary tube. The results showed that the content of ferulic acid in angelica preparation could be quantitatively determined in the range of 5-100ug \ ml, with good repeatability.

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Detection and analysis method of ferulic acid(1)

1. High performance liquid chromatography

The content of Ferulic Acid was determined by HPLC. The method is simple, rapid, accurate and precise. It is introduced in the literature that the mobile phase is mostly acid system, mainly including methanol water phosphoric acid system, methanol water glacial acetic acid system, methanol acetonitrile water glacial acetic acid system, etc. the amount of methanol can be adjusted properly in the experiment. The content of ferulic acid in Compound Ginkgo Oral Liquid was determined by HPLC. The Mixed Tocopherols OilFerulic Acid was methanol: 1% glacial acetic acid (45:55). The detection wavelength was 320nm, the flow rate was 1.0ml/min, and the column temperature was 25 ℃. The linear relationship of ferulic acid oxygen intake was good in the range of 0.176-0.88ug.

2. Thin layer scanning

Thin N-Acetylneuraminic Acid is also one of the commonly used methods for the determination of ferulic acid. The method is rapid, but its sensitivity is not ideal. Ji Shengguo et al. Determined the content of ferulic acid in Jiangzhi Tongmai oral liquid by TLC scanning. Using Flax lignans acetic acid chloroform (6:0.5:3.5) as developing agent, the single wavelength reflection hair saw tooth scanning was carried out with the scanning wavelength of 325nm. Good stability.

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Introduction to the citrus aurantium extract

Citrus Aurantium Extract and its cultivated varieties or dried young fruit of Citrus sinensis Osbeck are the extracts of Fructus aurantium L. From May to June, collect the self falling fruits, remove the impurities, dry them in the sun or dry them at low temperature. The product is hemispherical in shape, with a diameter of 3-5cm. The Acerola Cherry Extract is brown or tan, with granular protuberances, concave oil chambers at the top of protuberances, and obvious style vestiges or pedicel marks. In the section, the peel is yellow white, smooth and slightly uplifted, 0.4-1.3cm thick, with 1-2 rows of oil chambers scattered on the edge. Matcha Green Tea Powder is hard and not easy to break. There are 7-12, a few to 15, and the juice sac is brown to tan in dry shrinkage. The air is fragrant, bitter and slightly sour. From May to June, collect the self falling fruits, remove the impurities, dry them in the sun or dry them at low temperature. It is better to have hard quality and strong fragrance. Mainly distributed in Jiangsu, Zhejiang, Guangdong, Guizhou, Sichuan, Jiangxi and other places.

Gardenia Yellow, melting point 184-1850c, hydrochloride crystallization 151-152, soluble in water. Heavy tartrate, melting point 188-189, soluble in water, insoluble in ethanol, almost insoluble in chloroform and ether. Hydrochloride, colorless crystal (ethanol ether), melting point 166-167. Racemization is easy to occur in the separation of strong acid and strong base ion exchange resin.

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Application of mango leaf extract

Modern pharmacological research shows that the chemical components of Mangifera Indica Extract mainly include mangiferin, high mangiferin, quercetin, gallic acid, catechol, shikimic acid, kaempferic acid, ellagic acid, platyclonene and volatile components. Mango leaf extract has antiasthmatic, antitussive and expectorant effects. However, there is no research report on mango leaf extract in the prevention and treatment of metabolic syndrome. Vine Tea Extract has a good effect in the treatment of chronic bronchitis. It is the main effective component in the treatment of hepatitis and the antiviral active component in rhizome of Anemarrhena asphodeloides.

Modern medical research has confirmed that Flax lignans also has many pharmacological effects, such as anti-oxidation, anti-inflammatory, bacteriostasis, anti radiation, prevention and treatment of skin aging, hypoglycemia, hypouricemia, anti-tumor, immune regulation, cholagogic, inhibition of central nervous system, anti-inflammatory and N-Acetylneuraminic Acid, alleviation of sacral radiculopathy caused by HSV-2 virus, etc. it has been used in Pharmacopoeia of China and many traditional Chinese medicines Mangiferin content is often used as quality control index in the quality standard of Chinese patent medicine.

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Antitumor and antiviral effects of bitter melon extract

As early as 1982, scientists have found that the crude extract of Momordica charantia has the function of enhancing the body’s immunity and Capsicum Oleoresin. Whether the balsam pear juice or balsam pear extract was given, the level of serum hemagglutination antibody, the content of serum Bitter Melon Extract and the phagocytic ability of white blood cells in mice were significantly increased, Astaxanthin Supplier and the immune function of mice was enhanced. This may be one of the reasons why the crude extract of Momordica charantia has antitumor effect.

Momordica charantia Sweet Potato Powder also has the function of anti leukaemia and anti-virus. A protein factor purified from Momordica charantia can have long-term or short-term killing activity on a variety of tumor cells.

In addition, scientists purified a new protein MAP30 from Momordica charantia fruits and seeds, which has anti HIV effect. The researchers cultured human lung fibroblasts in the culture solution containing MAP30. After 24-48 hours of inoculation of herpes simplex virus, they found that only 0.1-0.2 μ M / L MAP30 was needed for the virus to have a useful inhibition effect, while acyclovir (an anti herpes simplex drug in Changchuan) required 0.2 μ m for different types of herpes simplex virus/ And 1.6 μ M / L, which shows that MAP30 has high antiviral effect and is very useful for the treatment of herpes infection.

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Background and overview of mango leaf extract(2)

Mangiferin can improve hyperinsulinemia of KK-Ay mice. Flax lignans Based on the above results, mangiferin may show antidiabetic activity through insulin sensitization.

In the prior art, the preparation method of Mango Leaf Extract adopts the method of concentration and drying after extraction. The content of mangiferin is low, which belongs to the crude method with low potency. The refining Mangiferin include the use of macroporous adsorption resin or silica gel chromatography. Silica gel chromatography is not suitable for large-scale production with a large number of organic solvents. In the past, the purification method of macroporous adsorption resin used high concentration ethanol for elution, but it is difficult to get Gardenia Yellow leaf extract with mangiferin content of more than 50%. More importantly, the eluted mango leaf extract can not be prevented The effect of diabetes and lipid-lowering.

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Background and overview of mango leaf extract(1)

Mango leaves are the leaves of Mangifera endical. According to the dictionary of traditional Chinese medicine(Pueraria Mirifica Extract): Mango folate, sweet, cool. It can relieve stagnation of Qi, remove the accumulation of Sha, treat abdominal pain and distention due to stagnation of heat, and wash away ulcers. Mangiferin, the main component of Mango Leaf Extract, is the main effective component in the treatment of respiratory diseases, and has been found in other families and genera. Modern pharmacological studies show that mango leaf extract has the functions of antiasthmatic, antitussive, expectorant, immune, anti-inflammatory, analgesic, antioxidant, anti diabetes, Ginkgo Biloba Extract and antiviral. At present, mango cough tablet, mango cough capsule, honeysuckle mango capsule and honeysuckle mango tablet have been marketed in China, and mangiferin is the effective component of mango leaf extract.

Mangiferin can reduce the Bitter Melon Extract level of KK-Ay mice, but has no effect on the blood glucose level of normal mice, suggesting that mangiferin can be used to treat non-insulin-dependent diabetes.

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