标签： Ferulic Acid

Ferulic Acid is found in the natural plant Angelica sinensis, which is used as an edible traditional Chinese medicine. Therefore, security is relatively high. Modern studies have shown that ferulic acid can be absorbed by the human body and can be discharged in time from the urine without accumulation in the human body and causing accumulative toxicity. In particular, Capsicum Oleoresin is easy to metabolize, has very low toxicity and is relatively safe to use. Because of this, ferulic acid is widely used in medicine and food industry.

Conclusion: Sweet Potato Powder is recommended as an effective and safe whitening and antioxidant ingredient. However, it should be noted that the choice of such whitening products should be ferulic acid, rather than ferulic acid or ferulic acid ester ingredients. Because that affects the activity and efficiency of Gardenia Yellow. In addition, the development of products containing ferulic acid is a challenge for formulators, requiring a deep foundation in cosmetics formula development.

Ferulic Acid is widely found in plants in nature. Its chemical name is 4-hydroxy-methoxy cinnamic acid. It is a kind of phenolic acid widely found in plants. Because ferulic acid is mostly extracted from Angelica, and contains ferulic acid in chuanxiong, horseman, cohosh and other traditional Chinese medicines, Mixed Tocopherols Oil is one of the derivatives of cinnamic acid. Ferulic acid, of course, is in plants.

Flax lignans seldom exists as a free state, but mainly exists in plants in combination with oligosaccharides, polyamines, lipids and polysaccharides. N-Acetylneuraminic Acid sodium and ferulic acid ester, these two derivatives, basically embody and maintain the biological characteristics of ferulic acid.

Ferulic Acid is used more as a drug and is widely used in the food industry as an antioxidant. In recent years, ferulic acid has also begun to be used in the cosmetics industry. Flax lignans in the skin care industry is mainly based on the whitening and antioxidant effects of ferulic acid:

It has been reported that ferulic acid can inhibit or reduce the proliferation activity of melanocytes. The number of melanocyte can be reduced from 117±23/mm2 to 39±7/ mm2 by using 0.1 ~ 0.5% ferulic acid solution. At the same time, N-Acetylneuraminic Acid can also inhibit the activity of tyrosinase, and the inhibition rate of ferulic acid solution with a concentration of 5mmol/L to the activity of tyrosinase is as high as 86%. Even with a concentration of 0.5mmol/L ferulic acid solution, the inhibition rate of tyrosinase activity can reach about 35%.

In addition, Sweet Potato Powder also has scavenging oxygen free radicals and good antioxidant effects. In addition, it has been reported that ferulic acid has the ability of sunscreen, and ferulic acid can effectively absorb ultraviolet radiation in the wavelength range of 290 ~ 330nm to prevent or reduce the damage caused by ultraviolet radiation at this wavelength to the skin.

Ferulic Acid, with the chemical name of 4-hydroxy-3-methoxycinnamic acid, is one of the derivatives of cinnamic acid (also known as cinnamic acid, 3-phenyl-2-acrylic acid, molecular structure). Ferulic acid was initially found in seeds and leaves of plants. It is a phenolic acid widely existing in plants. Barley Grass Powder combines with polysaccharides and proteins in cell wall to form the skeleton of cell wall.

Its content in ferula, Gardenia Yellow, chuanxiong, Cimicifuga, Zizyphus Spinosae and other traditional Chinese medicine is high, which is one of the effective components of these traditional Chinese medicine, and has been used as one of the quality indicators of Chinese patent medicine. The content of Mangiferin in coffee, rice husk, vanilla bean, wheat bran and rice bran was also higher. In recent years, many ferulic acid and its derivatives have been found to have pharmacological and biological activities with low toxicity. Therefore, they are widely used in medicine, health care products, cosmetics raw materials and food additives.

Hirabayashi et Capsicum Oleoresin. Found that after the megaphilic cells of experimental mice were infected with influenza virus, the blank control was set without treatment, and the experimental group was treated with ferulic acid and isoferulic acid. Analysis of the results showed that the production of interferon in the experimental group decreased rapidly. In recent years, there are many reports that ferulic acid has a significant inhibitory effect on influenza virus (Barley Grass Powder), respiratory syncytial virus (RSV) and HIV. In the same cell line, the effect of ferulic acid on inflammatory protein was studied. The results showed that ferulic acid could reduce the production of the protein rapidly. Among them, ferulic acid has inhibitory effect on HIV, so it is possible that Sweet Potato Powder may become a future chemotherapeutic agent. It is speculated that the inhibitory mechanism of ferulic acid on virus is related to its ability to reduce the activity of xanthine oxidase. It is suggested that the antibacterial function of Ferulic Acid is mainly due to its strong inhibitory effect on n-ethyluginostase in bacteria.

Radiation induced organ failure is largely caused by chronic peroxide damage. Radiation damage to the body can be divided into direct damage and Mangiferin. Direct damage directly causes the breakage of some sensitive molecules in the cell; indirect damage causes the radiolysis of water, which leads to the increase of intracellular reactive oxygen species and the change of subcellular structure. Therefore, antioxidants are widely used in the treatment of radiation injury. In order to protect cells from reactive oxygen species (ROS), it is necessary to maintain stable endogenous sulfhydryl pool, especially glutathione (Gardenia Yellow) and nicotinamide adenine dinucleotide phosphate (NADPH). Glutathione provides reduction equivalent for the conversion of hydrogen peroxide and lipid peroxide into water and lipid alcohol, and protects the sulfhydryl protein group from oxidative damage. The rate limiting reaction of glutathione biosynthesis is catalyzed by glutamate cysteine ligase (Flax lignans), which is composed of a catalytic subunit (GCLC) and a regulatory subunit (GCLM). Nicotinamide adenine dinucleotide phosphate is an important antioxidant component in tissues. It can maintain the redox potential of cells by reducing the reduction equivalent of glutathione reductase and thioredoxin.

As a phenolic plant component, Ferulic Acid has strong antioxidant activity, which has a great promoting effect on human health. Ferulic acid can significantly increase the content of glutathione and nicotinamide adenine dinucleotide phosphate in radiation-induced endothelial cells, which has protective effect on irradiated endothelial cells. Heme oxygenase is an antioxidant enzyme. It can convert heme into biliverdin, and finally into antioxidant bilirubin. Ferulic acid can regulate the expression of heme oxygenase, thus playing a protective role in radiation protection.

Alias: 3-methoxy-4-hydroxycinnamic acid

Physical properties: there are two types: Flax lignans and trans. The CIS is yellow oil, the Trans is square crystal or fiber crystal. The melting point is 174 ℃. It is soluble in hot water, ethanol and ethyl acetate, slightly soluble in ether, and hardly soluble in benzene and petroleum ether.

Pharmacological effects: Ferulic Acid (sodium ferulate) has the functions of anti platelet aggregation, inhibiting the release of 5-hydroxytryptamine, inhibiting the production of thromboxane A2 (TXA2), enhancing prostaglandin activity, N-Acetylneuraminic Acid, and relieving vasospasm. It is the basic raw material for the production of drugs for the treatment of cardiovascular and cerebrovascular diseases and leukopenia. Such as Xinxuekang, Limai capsule, madam oral liquid, etc., Mixed Tocopherols Oil can also play the role of bodybuilding and skin protection in human body.

Plant sources: ferula asafetida L., Ligusticum chuanxiong Hort. Rhizome, Lycopodium selago L., Equisetum hiemal L., Cactus Extract, Oryza sativa L., testa, Allium cepa, Liliaceae 50. Root, bulb, leaf, Raphanus sativus L. root, Catalpa ovata g. don bark, Anthemis nobilis L. flower, white flower, and Bougainvillea glabrachoisy root.

Ferula assafetida L., Ligusticum chuanxiong Hort. Rhizome, Lycopodium selagol. Whole grass, Equisetum Hiemale L. whole grass, Cistanche Tubulosa Extract rhizome, Oryza sativa L. seed coat, Allium onion Cepa L. root, corm, leaf, Raphanus sativus L. root, Cruciferae plant, Catalpa ovata g. don bark, Anthemis nobilis L. flower, Compositae plant, bougainvillea glabrachoisy root.

Ferulic Acid is one of the derivatives of cinnamic acid (also known as cinnamic acid, 3-phenyl-2-acrylic acid, molecular structure). Ferulic acid was originally found in the seeds and leaves of plants. Ferulic acid is a phenolic acid widely found in plants. Purple Sweet Potato Powder combines with polysaccharides and proteins in the cell wall to form the skeleton of cell wall.

Antibacterial and antiviral functions

Hirabayashi et al. Found that the experimental mice were infected with influenza virus, and the control group was treated with Ferulic Acid and isoferulic acid. Analysis of the results showed that the production of interferon in the experimental group decreased rapidly. In recent years, there are many reports that ferulic acid has a significant inhibitory effect on cold virus (IV), respiratory syncytial virus (Spirulina Powder) and HIV. In the same cell line, we studied the relationship between ferulic acid and inflammatory protein. Results Flax lignans can dramatically reduce the production of egg white. Among them, ferulic acid has an inhibitory effect on HIV, which makes it possible for N-Acetylneuraminic Acid to become a chemical therapeutic agent in the future. It is speculated that the mechanism of ferulic acid’s inhibition on the virus is related to its ability to reduce the activity of xanthine oxidase, which is due to the fact that ferulic acid can generally lead to the occurrence of some inflammation. It is speculated that ferulic acid’s antibacterial function is mainly due to its strong inhibition on n-ethylhexyltransferase in bacteria.

Antioxidant function

Metabolism is the characteristic of living body. At the same time, living body is always attacked by a Ferulic Acidctive oxygen substances (molecules or free radicals directly or indirectly transformed from molecular oxygen, which are more active than molecular oxygen). Free radicals (also known as free radicals, which refer to the Capsicum Oleoresin, atomic groups or molecules in special states with unpaired electrons in the outer orbit), Both of these two substances can directly participate in the formation of tumor or induce the production of carcinogens, change the DNA of life body, activate the proto oncogene, so as to promote the body to produce cancer cells and reduce the Sweet Potato Powder is the key link of prevention and treatment of related diseases. Some studies have shown that ferulic acid can kill free radicals skillfully and restore the normal functions of living bodies. Ferulic acid can inhibit the enzymes that produce free radicals in living bodies. On this basis, it can also increase the enzymes that clear free radicals. At the same time, Mixed Tocopherols Oil can greatly enhance the activities of waking reductase and glutathione transferase, and control the proportion of active tyrosinase. Zhou et al. Showed that ferulic acid had significant antioxidant effect and had good scavenging effect on ammonia peroxide, superoxide radical, hydroxyl radical and nitroperoxide.